Biology Part 2 - Quick Guide

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Biology - Classification of Organisms

Introduction

• The technique of classifying organisms is known as Taxonomy.

• Taxonomy is made up of two words i.e. ‘Taxis,’ which means ‘arrangement’ and ‘Nomos,’ which means ‘method.’

• The Swedish botanist Carolus (Carl) Linneaeus has developed the modern taxonomic system.

• Linneaeus has developed the following hierarchy of groups to explain the taxonomy −

• In this hierarchy, Domain is the highest order and the broadest category and Species is the lowest order category.

• Further based on the difference between eukaryotes and prokaryotes (cells) ‘Domains’ classified into three broad categories namely −

• Archea(Archeabacteria) − It comprises the bacteria that live in extreme environments.

  • Eubacteria − It comprises the bacteria that found in everyday life.

  • Eukaryote − It comprises almost all the world's visible living things.

• The above given three domains are further categorized into Five following Kingdoms −

• Let’s discuss each kingdom in brief −

  • Monera − It comprises the unicellular organisms, e.g. bacteria.

  • Protista − Similar to monera (unicellular), but more developed and complex. It contains nucleus.

  • Plantae − All plants from smallest (such as algae) to the largest (such as Pine, Eucalyptus trees, etc.) are studied under this kingdom.

  • Fungi − It is a group of eukaryotic organisms that comprises microorganisms such as yeasts, molds, and mushrooms. The organisms of this kingdom do not make their food, they are basically parasites.

  • Animalia − It includes all the multicellular and eukaryotic organisms (of animal group). It is also known as Metazoa.

Binomial Nomenclature

• The naming culture (of different organisms) practiced uniformly across the world is known as binomial nomenclature.

• Binomial Nomenclature largely consists of two words – the first word beginning with a capital letter and known as genus (of the organism) and the second word begins with lower case letter and defines the species of the organism.

• Binomial Nomenclature must be written in italic and also known as scientific name.

• For example, the binomial nomenclature of human is - Homo sapiens; tiger - Panthera tigris, etc.

Eukaryotes and Prokaryotes

• Cells are fundamentally categorized by prokaryotes and eukaryotes.

Prokaryotes

• Prokaryotes are the smallest and simplest type of cells.

• Prokaryotes have no true nucleus and no membrane-bound organelles. E.g. Bacteria.

• Prokaryotes’ Genome consists of single chromosome.

• Reproduction is asexual; basically mitosis type.

Eukaryotes

• Eukaryotes are complex in structure.

• Eukaryotes have nuclei and membrane-bound organelles.

• Eukaryotes’ Genome consists of numerous chromosomes.

• Reproduction is sexual; by mitosis and meiosis.

Biology - Cell Division

Introduction

• The process of division of parent cell into two or more daughter cells is known as cell division.

• In early 1880s, Flemming first observed the process of cell division.

• Following are the three types of cell division −

  • Amitosis

  • Mitosis &

  • Meiosis

• Let’s discuss each of them in brief −

Amitosis

• Parent cell gets divided into two parts, and each of them grows as a new complete organism.

• Amitosis can be seen in less developed organisms. E.g. bacteria

• Amitosis is also known as binary fission.

• There is no stage of division, cell directly gets divided into two new organisms.

Mitosis

• The process of division of parent cell into two new identical cells is known as mitosis.

• In both the new cells, the number of chromosomes remain same.

• Mitosis (cell division) occurs only in eukaryotic cells.

• In mitosis, the division of the nucleus is preceded by the S stage (i.e. interphase - during this phase, the DNA is replicated).

• After the interphase, the cytokinesis process begins, which divides the cytoplasm, cell organelles, and cell membrane into two new cells.

• The process of mitosis is divided into the following stages −

  • Prophase

  • Prometaphase

  • Metaphase

  • Anaphase

  • Telophase

• The stages of mitosis are described in the following image −

• Let’s discuss each of them in brief −

Prophase

• During the prophase, cell prepares to get divided.

• The prophase process is also known as chromosome condensation, as chromatin fibers condense into discrete chromosomes.

• Each chromosome has two chromatids and these two chromatids are joined at a place known as centromere.

Prometaphase

• In this phase, the nuclear envelope gets disintegrated into small membrane vesicles.

Metaphase

• In this phase, the two centrosomes start pulling the chromosomes towards opposite ends of the cell and ensure the equitable distribution of chromosomes.

Anaphase

• In this phase two identical daughter chromosomes are formed.

Telophase

• Telo is a Greek word meaning ‘end’.

• In this phase, the nuclear envelop gets broken and a new nuclear envelop forms.

• The new envelope gets formed around each set of separated daughter chromosomes; parallel, the nucleolus reappears.

• Likewise, the mitosis is complete.

Cytokinesis

• Cytokinesis, technically, is not a phase of mitosis, but rather a distinct process, essential for completing the cell division.

• In this phase, cytoplasm begins to divide and completed with the development of two new identical cells.

Meiosis

• Meiosis is a typical type of cell division in which the chromosome number gets reduced by half, creating four haploid cells. Each cell is genetically distinct from the parent cell.

• Meiosis cell division process occurs in all sexually reproducing single-celled and multicellular eukaryotes, including plants, animals, and fungi.

• Meiosis cell division is primarily categorized as Meiosis I and Meiosis II.

Biology - Virus

Introduction

• A virus is a micro infectious agent, which is found as parasite in the living cells of other organisms.

• Virus replicates swiftly inside the living cells of other organisms.

• Virus is a Latin term meaning ‘poison’ and other ‘noxious’ liquids.

• Viruses can infect any type of life forms, ranging from animals and plants to microorganisms, including bacteria and archaea.

• The study of viruses is known as virology.

• Virus is first discovered by Dmitri Ivanovsky in 1892.

• Virus has the properties of living as well non-living.

• One of the living properties is – virus has either DNA or RNA (never both).

• One of the non-living properties is – virus has no protoplasm.

Types of Virus

• Based on parasitic nature, virus is categorized as −

  • Animal Virus

  • Plant Virus

  • Bacterial Virus

  • Archaeal Virus

Viral Diseases in Human Being

• Following are the list of diseases caused by virus in Human beings −

  • Chickenpox

  • Encephalitis

  • Influenza (or Flu)

  • Herpes (skin disease)

  • Human immunodeficiency virus (HIV/AIDS)

  • Human papillomavirus (HPV)

  • Infectious mononucleosis

  • Mumps (measles and rubella)

  • Shingles

  • Viral gastroenteritis (stomach flu)

  • Viral hepatitis

  • Viral meningitis

  • Viral pneumonia

Viral Diseases in Plants

• Following are the list of diseases caused by virus in plants −

  • Peanut - Stunt Virus

  • Maize - Mosaic Virus

  • Lettuce - Mosaic Virus

  • Cauliflower - Mosaic Virus

  • Sugarcane - Mosaic Virus

  • Cucumber - Mosaic Virus

  • Tobacco - Mosaic Virus

  • Tomato - Twisted leaf disease

  • Lady finger - Yellow vein mosaic

Viral Diseases in Animals

• Following are the list of diseases caused by virus in animals −

  • Cow – Herpes (Herpes virus)

  • Buffalo – Small pox (Poxverdi orthopox)

  • Dog – Rabies (Stereit virus)

Biology - Bacteria

Introduction

• Bacteria normally comprises a large number of prokaryotic microorganisms.

• Bacteria most probably were among the first life that formed to appear on the Earth.

• Bacteria belong to Monera kingdom.

• Bacteria usually inhabit in all range of environments, such as soil, water, acidic hot springs, radioactive waste, and the deep portions of Earth's crust.

• The study of bacteria is known as bacteriology.

• Bacteria play an important role in many stages of the nutrient cycle by recycling nutrients including the fixation of nitrogen from the atmosphere.

• Bacteria grow to a fixed size and after maturity reproduce through asexual reproduction i.e. basically binary fission.

• Under favorable conditions, bacteria can grow and divide very swiftly, and the bacterial populations can double merely in every 9.8 minutes.

• When viruses that infect bacteria is known as Bacteriophages.

• In order to modify themselves (to survive in the adverse environment), Bacteria frequently secrete chemicals into their environment.

Advantages of Bacteria

• Bacteria are advantageous in many ways, such as −

  • Bacteria help in atmospheric nitrogen fixation.

  • Bacteria decompose dead plants and animals and clean the environment.

  • Bacteria are the major element that convert milk into curd and wine into vinegar.

  • Some specific types of bacteria are used in making proteins.

  • Some types of bacteria are also used as pesticides.

Disadvantages of Bacteria

• Bacteria cause many diseases and infection to living organisms.

Bacterial Diseases

• Bacteria cause many diseases, significant of them are −

  • Anthrax - caused by Bacillus anthracis

  • Brucellosis - caused by Brucella abortus

  • Botulism - caused by Clostridium botulinum

  • Coliform diseases - caused by Escherichia coli

  • Leprosy - caused by Mycobacterium leprae

  • Plague - caused by Yersinia pestis

  • Typhoid fever - caused by Salmonella typhi

  • Trachoma - caused by Chlamydia trachomatis

  • Diphtheria - caused by Corynebacterium diphtheria

  • Tetanus - caused by Clostridium tetani

  • Tuberculosis - caused by Mycobacterium bovis

  • Cholera - caused by Vibrio cholera

  • Syphilis - caused by Treponema pallidum

  • Whooping cough - caused by Bordetella pertussis

  • Gonrhoea - caused by Gonococcus

  • Potato wilt - caused by Pseudomonas solanacearum

  • Blight of rice - caused by Xanthomonas orzae

  • Fire blight of apple - caused by Invenia

Biology - Fungi

Introduction

• Fungi are the members of eukaryotic organisms, which includes microorganisms such as molds, yeasts, and mushrooms.

• Fungi do not photosynthesize rather they obtain their food by absorbing the dissolved molecules, usually by secreting digestive enzymes into their environment.

• Fungi are found in almost every part of the world, and they can grow in a wide range of habitats, ranging from extreme environments (such as deserts) to mild (such as temperate region).

• Fungi are the primary decomposers in most of the ecological systems.

• The study of fungi is known as mycology.

• Fungi have membrane-bound cytoplasmic organelles, for example mitochondria, sterol-containing membranes, and ribosomes.

• Fungi have also a cell wall and vacuoles (property of plants).

• Fungi have no chloroplast and they are heterotrophic organisms (property of animals); likewise, fungi have both the properties of plants and animals.

Advantages of Fungi

• Fungi have medicinal advantages, as they have been used for the manufacturing of antibiotics and various enzymes.

• One of the most popular antibiotic drug penicillin is manufactured from the fungus Penicillium.

• The ‘shiitake,’ one of the types of mushroom is a source of a clinical drug known as Lentinan.

• Fungi are also used as the biological pesticides to control plant diseases, weeds, and insect pests.

• In Japan, Lentinan is used to treat in cancer disease.

• As they feed the dead organic matters, fungi recycle about 85 percent of the carbon from dead organic matter; likewise, fungi release the locked-up nutrients so that they can be used by other organisms.

• Many varieties of fungi such as oyster mushrooms, straw mushrooms, shiitakes, milk mushrooms, truffles, and black trumpets are edible.

• Portobello mushrooms and Button mushrooms are usually used in soups and salads.

• Fungi are also used to produce industrial chemicals, including citric, malic and lactic acids.

• Fungi are frequently used to produce industrial chemicals, such as citric, malic and lactic acids.

Disadvantages of Fungi

• Some mushrooms, though they look like edible mushrooms, but they are poisonous that may cause even death to the person who ate.

• Some Fungi can infiltrate the external layers of the human bodies and cause itching and rashes problems.

• Certain fungi appear on food stuffs and destroy them shortly.

• Fungi also cause various diseases to animals (including humans) as well as plants.

Fungal Diseases

• Fungi cause many diseases, significant of them are −

  • Athlete’s foot - Taenia pedis

  • Asthma - Aspergillus fumigatus

  • Ring work - Trichophyton

  • Meningitis - Cryptococcus neoformans

  • Baldness - Taenia captis

  • Dermatophilosis - Dermatophilus congolensis

  • Wart disease of potato - Synchytrium endobioticum

  • Rhinosporidiosis - Rhinosporidium seeberi

  • Rust of wheat - Puccinia graminis tritici

  • Red rot of sugarcane - Colletotrichurn falcatum

Biology - The Roots

Introduction

• Root is the most essential part of a plant that grows down to the soil and water.

• Root avoid the sunlight, as it grows down to soil and water, and absorbs mineral salt and water from the soil.

• However, some typical roots are also aerial or aerating, that grow up above the ground or especially above the water.

• Roots do not have leaves, buds, and nodes.

Functions of the Roots

• The roots absorb mineral salts and water from the soil then supply them to other parts of the plants.

• Roots provide foundation to plants and keep them static.

• Some roots absorb foods for the contingency period; e.g. radish, carrot, etc.

Types of Roots

• Primarily, roots are classified as −

  • Tap Root

  • Fibrous Root

  • Adventitious Root

  • Let’s discuss them in brief −

Tap Root

• There is a main root (see the image given below) that grows faster and it has many branches. Usually, it occurs in dicotyledon plants.

Fibrous Roots

• There is as such no primary root rather there are numerous roots of similar shape, thickness, and size.

• It is typical feature of monocots (plant).

Adventitious Root

• A typical root that grows from any part of a plant except the primary root part.

• Adventitious root may be underground or may aerial.

Modified Taproots

• The following table illustrates some typical examples of modified taproots −

Taproots	Examples
Conical shape	Carrot
Napiform	Beet root
Fusiform	Radish
Pneumatophores	Sundari plants
Pneumatophores	Sundari plants

Modified Adventitious Roots

• The following table illustrates some typical examples of modified adventitious roots −

Adventitious Roots	Examples
Aerial root	Orcede
Parasitic root	Kascutta
Moniliform root	Grapes
Prop root	Banyan tree
Stilt root	Sugarcane, maize, etc.

• Note − Tuber is a stem that grow horizontally under the soil and develop roots on their lower surfaces. Major function of this swollen stem is to store food and nutrients. E.g. potato, onion, etc.

Biology - The Plant Stem

Introduction

• A stem is one of the main structural axes of a vascular plant.

• The stem, structurally, is categorized into nodes and internodes (see the image given below).

• The other term used for the stem is shoot, but there is difference between stem and shoot, i.e. stem includes only stem part, whereas, shoot includes stem, leaf, flower, etc. (shoot term basically used for new plant growth).

Functions of Stem

• Following are the significant functions of a stem −

  • Stems keep plant upright and support leaves, flowers, and fruits.

  • Stems comprise xylem and phloem (tissues) that transport fluids and nutrients between root and shoot.

  • Stems store nutrients and produce new cells and tissues.

Types of Stems

• Stems are usually categorized as −

Underground Stem

• The stem that grows inside the soil is known as underground stem. E.g. Potato.

• Such type of stems store food for contingency period.

Subaerial Stem

• The stem, which partial remains inside the soil and partial above (i.e. in the air), is known as subaerial stem. E.g. Cynodon

Aerial Stem

• The stem, which entirely remains in the air (i.e. out-side of soil or water), is known as aerial stem. E.g. passiflora, grapes, etc.

Modification of Stems

• Sometimes, stems perform some specific task (other than their regular task), for which they change their shapes and sizes.

• The following table illustrates some of the examples that modified stems −

Location	Type	Example
Underground Modified Stem	Bulb	Garlic, Onion, etc.
	Corm	Saffron, Crocus, etc.
	Stem tuber	Potato
	Rhizome	Ginger
Subaerial Modified Stem	Stolon	Jasmin, Straberi, etc.
	Offset	Water plant, Pistia, etc.
	Sucker	Roses, Musa, etc.
	Runner	Mereilia, Cynodon, etc.
Aerial Modified Stem	Stem thorn	Lemon, Citrus
	Stem tendril	Grape
	Phylloclade	Cactus, Opuntia
	Bulbils	Ruscus, Agave
	Tendril	Passiflora

Biology - The Plant Leaf

Introduction

• Leaves, usually, are thin and flattened organs, borne above ground.

• There are varieties of leaves in terms of shapes, sizes, and textures. Likewise, different species of plants have different shapes, sizes, and textures of leaves.

• Some varieties of leaves are thick and juicy (especially of succulent plants).

• Leaves are usually of green color because of the presence of chloroplast.

• However, some show plants have colorful leaves (see image given below) −

• Succulent plants often have thick juicy leaves, but some leaves are without major photosynthetic function and may be dead at maturity, as in some cataphylls and spines (see image given below).

Functions of Leaves

• Following are the major functions of leaves −

  • Leaves prepare food through photosynthesis.

  • Leaves are the most important parts through which plants respire.

  • Some leaves also store foods for the contingency period.

  • Leaves assist in reproduction and pollination.

  • Some leaves (especially of succulents plants – shown above), store chemical energy and water.

Modified Leaves

• To survive in an adverse environment, some of the plant species (especially leaves) modified themselves. Following are the list of such leaves −

• Spine leaves − Such leaves are look like spines, e.g. cactus plants (see image below).

• Bract leaves − Also known as pseudanthia (or false flowers), they are colorful leaves (see image below).

• Succulent leaves − These leaves store water and organic acids (see image below).

• Tendril leaves − Such leaves take the form of tendril and support plant to climb, e.g. pea plants (see image below).

• Scaly leaves − Some leaves modify themselves to protect buds known as scaly leaves, e.g. onion, garlic, etc. (see image below).

• Hook leaves − Such leaves modified as nails known as hook leaves, e.g. Bignonia (see image below).

• Pitcher leaves − Such leaves trap insects, e.g. pitcher plant. This is known as carnivorous plant (see image given below).

Biology - The Flowers

Introduction

• Flowers, as all of us interpret, are the beautiful parts of the plants, which beautify the environment by their enthralling colors and decisive fragrance.

• But flower is biologically the reproductive part of the plant.

Functions of Flower

• Following are the major functions of a flower −

  • The primary function of a flower is reproduction by the process of the union of sperm with eggs.

  • Depending upon the inherent property, flowers may facilitate selfing, which means fusion of sperm and egg from the same flower OR it may facilitate outcrossing, which means fusion of sperm and eggs from different individuals in the respective population.

  • The flowers produce diaspores (consisting of a seed or spore) without fertilization.

  • The flower is the site where gametophytes (is the sexual phase) develop.

  • Some of the flowers fascinate animals, birds, and other insects, so as to cause them to be vectors for the transfer of pollen.

  • After sometime of fertilization, the ovary of the flower develops into fruit that contains seeds.

Parts of Flower

• Primarily, the parts of a flower are categorized as −

  • The Vegetative Part and

  • The Reproductive Part

Let’s discuss them in brief −

Vegetative Part

• Calyx − Calyx is the outermost part that consists of some units known as sepals. It is typically of green color (see the image given below).

• Corolla − Corolla is the second (next to calyx) coil towards the apex, composed of units known as petals. Petals are usually thin, soft, and colored. It attracts insets and birds that ultimately help in pollination.

Reproductive Part

• Androecium − It consists stamens (the male sex organ). Every stamen has three parts namely Filament, Anther, and Connective.

• Gynoecium − It is the inner most part of the flower and consists of carpels (female sex organ).

• Carpels consist of ovary, style and stigma, collectively known as a pistil.

Pollination

• Pollination is basically the process of movement of pollen from the anthers to the stigma.

• When the pollens move to stigma of the same flower, it is known as self-pollination; on the other hand, if pollen move to stigma of other flower, it is known as cross-pollination.

Pollination Process

• Pollination process occurs through different mediums (see the table) −

Process (Pollination)	Medium (Pollination)
Anemophilous	By air
Entomophilous	By insects
Hydrophilous	By water
Chiropteriphilous	By bats
Malacophilous	By shells
Ornithophilous	By birds
Zoophilous	By animals

Biology - The Fruit

Introduction

• For the common people, fruits are nutritious and delicious edible things, but for a botanist, fruits are the seed-bearing structure found in flowering plants.

• During the ancient period or even today, many of the animals including human beings are dependent on fruits (for their survival).

• Likewise, fruit is usually fleshy seed-associated structures of a plant, which is edible in the raw state (not all types of fruits are edible, as some are poisonous) and tastes sweet or sour.

Structure of the Fruit

• The layer, usually, surrounding the seeds, is known as ‘pericarp.’

• Formed of ovary, pericarp is the edible part of fruit.

• The pericarp further classified as epicarp, mesocarp, and endocarp.

Seedless Fruits

• Some fruits are seedless (such as banana), which have pretty high commercial importance.

• Further, some fruits are scientifically developed seedless such as pineapples, grapes, etc.

Types of Fruits

• Based on the fertilization of the flowers, fruit is classified as −

• True Fruits − When the fruit forms in the ovary (of the flower) through fertilization is known as true fruit. E.g. strawberry.

• False Fruits − The fruits formed some other means (other than ovary), such as calyx, thalamus, corolla, etc. known as false fruits. E.g. pear, apple, etc.

• Further, because of verities and diversities, fruits are classified as −

• Simple fruit − It can be either dry fruit (such as coconut, walnut, etc.) or fleshy (such as gooseberry, tomato, etc.).

• Aggregate fruit − It is formed from single flowers, which have multiple carpels. E.g. raspberry.

• Multiple fruit − It is formed from a cluster of flowers, e.g. pineapple, mulberry, etc.

Fruits and their Edible Parts

• Following table illustrates the name of fruits and their edible parts −

Fruits	Edible Parts
Apple	Thalamus
Banana	Mesocarp
Coconut	Endosperm
Coriander	Thalamus
Chinese date	Epicarp & Mesocarp
Custurd apple	Pericarp
Guava	Pericarp
Grape	Pericarp
Ground nut	Seed leaves
Jack fruit	Sepals
Lemon	Juicy pore
Litchi	Pulpy aerial
Mango	Mesocarp
Mulberry	Bract, sepals
Orange	Juicy hair
Pear	Thalamus
Papaya	Pericarp
Tomato	Pericarp
Wood apple	Mesocarp

Biology - Plant Diseases

Introduction

• Like animals, plants also suffer from verities of diseases.

• The biological agents that causing diseases to plants are known as pathogens.

• Some of the common plant pathogens are −

  • Viruses

  • Bacteria

  • Fungi

  • Nematodes

• However, some non-pathogenic diseases (in plants) may also occur when the pH value, moisture, humidity, soil, etc. of soil change.

Viral Diseases in Plants

• The following table illustrates the major plant diseases caused by virus −

Disease	Plants Affected
Bud Blight	Soy beans
Curly top	Beans, tomato, sugar beets, etc.
Mosaic leaf	Tomato, tobacco, corn, legume, potato, pea, sugar beet, cucumber, maize, cauliflower, sugarcane, bean, etc.
Yellowing of leaf	Barley, sugar beet, potato, etc.
Spotted Wilt Virus	Tomato, capsicum, etc.
Chlorosis Virus	Tomato, capsicum, etc.

Bacterial Diseases in Plants

• The following table illustrates the major plant diseases caused by Bacteria −

Disease	Plants Affected
Blights	Vegetable crops, fruit trees, etc.
Bacterial wilts	Corn, tobacco, potatoes, alfalfa, tomatoes, etc.
Bacterial speck	Fruits and leaves of different plants
Cankers	Woody plants
Leaf spot	Cotton, beans, peas, etc.
Soft rots	Fleshy or succulent plant parts
Fire Bligh	Rosebushes, pome fruit trees, etc.

Fungal Diseases in Plants

• The following table illustrates the major plant diseases caused by Fungi −

Disease	Plants Affected
Cankers	Largely woody plants
Downy mildew	Grains, onions, cucumbers, alfalfa, etc.
Ergot	Rye, barley, wheat and other grasses
Powdery mildew	Grains, legumes
Tuber diseases	Potato, sweet potato, etc.
Rusts	Wheat, barley, rye, oats, etc.
Root rots	All types of plants
Scab	Wheat, barley, rye, potato, etc.
Smuts	Oats, barley, corn, wheat, grasses, etc.
Wilts	Potatoes, alfalfa, etc.
Cavity spot	Carrot
Leaf blight	Carrot
Ring spot	Brassicas

Diseases by Nematodes in Plants

• The following table illustrates the major plant diseases caused by Nematodes −

Disease	Plants Affected
Hairy root	Sugar beets, potatoes, soybeans, etc.
Root lesions	Different species of plants get affected
Root-knot	Tomatoes, peanuts, etc.

Biology - The Blood

Introduction

• The body fluid, found in almost all multicellular fauna (animals, birds, reptiles, etc.), and responsible for transporting necessary substances such as oxygen and nutrients to different parts of the body, is known as blood.

• Blood is basically connective tissue in the liquid form.

• Blood is largely composed of blood cells and plasma.

• Plasma constitutes about 55 percent of blood fluid.

• The pH value of blood pH is ranging between 7.35 and 7.45, i.e. slightly basic.

• Plasma is mostly water (i.e. 92% by volume) and contains dissipated proteins, glucose, hormones, mineral ions, and carbon dioxide.

• The blood of vertebrate (animals) appears bright red when its hemoglobin is oxygenated; when it is deoxygenated, it (blood) appears dark red.

• The blood accounts about 7 percent of the human body weight.

Functions of Blood

• Following are the significant functions of blood in the body −

  • Transports oxygen to tissues and cells located in different parts of the body

  • Supplies nutrients (e.g. glucose, fatty acids, amino acids, etc.) to tissues and cells located in different parts of the body

  • Removes waste products (e.g. carbon dioxide, urea, etc.) and help to throw outside the body

  • Also strengthens the immune system of the body

  • Regulates the body temperature.

Blood Terminologies

• Following are the significant terminologies that help to understand the blood −

• Blood Cells − based on color and function blood cells are classified as Red Blood Cells (RBC) and White Blood Cells (WBC).

• Red Blood Cells (see the image given below) consist of red pigments, known as haemoglobin, helps in oxygen transportation.

• White Blood Cells − (WBC) increase the immune system of the body, as it fights with the harmful germs that enter in your body.

• Platelets − Blood platelets have very important function i.e. it helps in blood clotting.

• Lymph − Lymph is a colorless fluid, which contains specialized lymphocytes; lymphocytes are accountable for the immune responses of the body.

Blood Vessels

• Following are the two major types of blood vessels −

  • Arteries and

  • Veins

• Let’s discuss them in brief −

Arteries

• The blood vessels that carry oxygen-rich blood (i.e. pure blood) from heart to all different parts of the body is known as arteries.

• Arteries usually have thick (vessels) wall because of having high blood pressure.

• All types of arteries transport oxygen rich blood from heart to different parts of the body except ‘Pulmonary Artery.’

• Pulmonary Artery carries carbon dioxide rich blood from heart to the lung for the oxygenation purpose.

• The tiny networks of blood vessels are known as capillaries. Capillaries are very thin structure.

Veins

• The blood vessels that carry carbon dioxide rich blood (i.e. impure blood) from different parts of the body back to heart are known as veins.

• Veins usually have comparatively thin (vessels) wall.

• The pulmonary vein carries oxygen rich blood from lung to the heart.

Biology - Blood Group

Introduction

• Based on the presence and absence of antibodies, the blood is classified into different groups.

• Further, while classification, the presence and absence of the inherited antigenic substances also considered.

• The types of blood groups are inherited and represent contributions from both the father and the mother.

ABO Blood Group System

• In human blood, usually, there are two antigens and antibodies.

• The two antigens are antigen A and antigen B.

• The two antibodies are antibody A and antibody B.

• The antigens are remaining in the red blood cells, whereas the antibodies are found in the serum.

• Based on the antigen property, the blood group of all human beings can be classified as −

  • Blood Group A − antigen A and antibody B

  • Blood Group B − antigen B and antibody A

  • Blood Group AB − antigen A and antigen B and no antibody

  • Blood Group O − no antigen, but antigen A as well as antibody B

• Consideration of the ABO system is the most imperative while transfusion of human blood.

• The ABO blood group systems were first discovered by Karl Landsteiner in 1901.

Rh Blood Group System

• The Rh system (the meaning of Rh is Rhesus) is another significant blood-group system. It is very important to match Rh system while blood transfusion.

• Rh antigen first studied in Rhesus monkeys; therefore, its name is given Rh factor/system.

• The person who does not have Rh antigen is known as Rh negative (Rh-ve) and the person who has the Rh antigen is known as Rh positive (Rh+ve).

Blood Transfusion

• Based on the above discussed two blood grouping system (i.e. ABO and Rh), the following table illustrates the possibilities of blood transfusion among different blood groups −

Recipient	Donor
	O-	O+	A-	A+	B-	B+	AB-	AB+
O-	Yes	No	No	No	No	No	No	No
O+	Yes	Yes	No	No	No	No	No	No
A-	Yes	No	Yes	No	No	No	No	No
A+	Yes	Yes	Yes	Yes	No	No	No	NO
B-	Yes	No	No	No	Yes	No	No	No
B+	Yes	Yes	No	No	Yes	Yes	No	No
AB-	Yes	No	Yes	No	Yes	No	Yes	No
AB+	Yes	Yes	Yes	Yes	Yes	Yes	Yes	Yes

Conclusion

• Based on the blood transfusion table given above the blood group O- is the universal donor, which can give blood to the person of any blood group.

• Secondly, the blood group AB+ is the universal recipient, as it can accept blood from the person of any blood group.

Biology - Human Brain

Introduction

• The brain of a human being is the central organ of the nervous system.

• The human brain consists of three parts namely the cerebrum, the brainstem and the cerebellum.

• The brain of a human being plays significant role, as it controls most of the activities of the human body.

• The brain is located inside the head, and protected by the skull bones.

• The brain consists of more than 86 billion neurons and almost equal number of other cells as well.

• Brain activity is made possible because of the interconnections of all the neurons that are linked together.

• The study of brain functions is known as neuroscience.

• An adult human brain weighs about 1.2 to 1.4 kg (i.e. average weight); which is about 2% of the total body weight.

Parts of Human Brain

• A human brain is primarily classified as the −

  • Forebrain

  • Midbrain

  • Hindbrain

• Forebrain is largely made up of cerebrum, thalamus, hypothalamus and pineal gland.

• Midbrain is largely made up of a portion of the brainstem.

• Hindbrain largely made up of the remaining brainstem, cerebellum and pons.

• Further, the (brain) hemisphere is conventionally classified into four lobes namely −

  • Frontal lobe

  • Parietal lobe

  • Temporal lobe

  • Occipital lobe

• The naming is done according to the skull bones that overlie them.

Cerebrum

• Divided into nearly symmetrical left and right hemispheres by a deep groove, the cerebrum is the largest part of the human brain.

• Cerebrum normally controls higher brain functions including language, logic, reasoning, and creativity.

Functions of Human Brain

• Major functions of human brain are −

  • Perceive or sense the signal coming from the (external) environment

  • Giving sense of feelings and emotion

  • Regulating and controlling the human behaviors

  • Regulating and controlling the physical action

  • Regulating the memory function

  • Process of thinking (and other cognitive process)

Biology - Skeleton System

Introduction

• The human Skeleton system is an internal structure that provides support and strength to human body.

• At the birth, there are about 300 bones, but over period time, specifically at maturity, the number of bones is 206.

Classification of Bones

• Human Skeleton system broadly classified into −

  • Axial skeleton and

  • Appendicular skeleton

• Let’s discuss them in brief −

Axial Skeleton

• With the total 80 bones, the axial skeleton consists of −

  • Vertebral column

  • Rib cage

  • Skull and other associated bones

Appendicular Skeleton

• With total 126 bones, the appendicular skeleton consists of −

  • Pectoral girdles

  • Upper limbs

  • Pelvic girdle

  • Pelvis

  • Lower limbs

• The image given below illustrates the names of the major bones of a human body.

Functions of Bones

• Following are the major functions of skeleton system −

  • It provides support to the body

  • It protects many parts of the body, e.g. the skull protects brain; the vertebrae protect spinal cord; the rib cage protects lungs; the spine protects heart, and the sternum protects blood vessels

  • The skeleton system helps in movement

  • The skeleton system helps in the production of blood cells

  • The skeleton system stores minerals

  • The skeleton system helps in endocrine regulation

Biology - Endocrine System

Introduction

• The endocrine system is study of the glands of an organism that secrete hormones directly into the circulatory system.

• The organs through which the life running hormones are secreted are known as endocrine glands or simply ductless glands.

• The hormone secreting glands are located in different parts of a human body (see the image given below).

• The scientific study of the endocrine system and its disorders is known as endocrinology.

Hormone

• The hormone is a complex but very important chemical substance released by the different glands in the body.

• The hormone is mainly made up of amino acid, catecholemines, and steroids.

• It is the hormone which is responsible for the overall growth and development; safety and security; behavior, sexual characteristics, and reproductive activities of a human body.

Types of Endocrine System

• Following are the major types of endocrine system −

  • Hypothalamus

  • Pineal Gland

  • Pituitary Gland

  • Thyroid Gland

  • Parathyroid Gland

  • Adrenal Gland

  • Pancreas Gland

  • Reproductive Gland (Ovaries & Testes Glands)

• Let’s discuss these glands in brief −

Hypothalamus

• It is located at the base of the brain.

• It releases Growth hormone-releasing hormone, Somatostatin hormone, etc., important for the growth.

Pineal Gland

• It is located at the base of the brain.

• It releases melatonin hormone helpful in lowering the core body temperature.

Pituitary Gland

• With the size of a pea, the pituitary gland is found at the base of the human brain.

• The average weight of pituitary gland is about 0.5 grams.

• It is also known as hypophysis.

• Following are the hormones secreted by the pituitary gland −

  • Growth hormone (somatotropin) − It is abbreviated as GH and it stimulates growth and cell reproduction.

  • Thyroid-stimulating hormone (thyrotropin) − It is abbreviated as THS and it stimulates iodine absorption by thyroid gland.

  • Adrenocorticotropic hormone (corticotropin) − It is abbreviated as ACTH and it stimulates corticosteroid and androgen.

  • Beta-endorphin − it inhibits perception of pain.

  • Prolactin − it stimulates milk synthesis and release from mammary glands.

Thyroid Gland

• Thyroid gland is located just below the larynx in the throat (pharynx).

• The hormone secreted by the thyroid gland is known as thyroxine.

• Following are the important hormones secreted by the thyroid gland −

  • Triiodothyronine(T3) − It stimulated body oxygen and energy consumption. It also promotes protein synthesis.

  • Thyroxine − It increases the basal metabolic rate.

  • Calcitonin − It stimulates osteoblasts and bone construction.

Parathyroid Gland

• It is located in the neck of a human body.

• It releases parathyroid hormone that helps in regulating the amount of calcium in the blood as well as within the bones.

Adrenal Gland

• Adrenal gland is found above the kidneys.

• It releases the following major hormones −

  • Glucocorticoids − It stimulates gluconeogenesis and fat-breakdown in adipose tissue.

  • Mineralocorticoids − It stimulates active sodium reabsorption in kidneys.

  • Adrenaline − It increases the supply of oxygen and glucose to the brain and muscles.

  • Dopamine − It increases heart rate and blood pressure.

  • Enkephalin − It regulates pain.

Pancreas Gland

• Pancreas gland is located in the abdominal cavity (behind the stomach).

• Pancreas is a mixocrine gland, as it releases both enzymes and hormones.

• It releases the following major hormones −

  • Insulin − It regulates the metabolism of carbohydrates, proteins, and fats.

  • Glucagon − It raises the concentration of glucose in the bloodstream.

  • Somatostatin − It inhibits release of insulin and glucagon.

Reproductive Gland

• The reproductive gland is classified as Testes in Male and Ovary in Female.

• Testes releases androgens (hormone) that help in strengthening muscle, increasing bone density, maturation of sex organs.

• Ovary releases progesterone hormone that helps during pregnancy period.

Biology - Endocrine Diseases

Introduction

• The diseases caused by either the deficiency or excessive of hormones is known as endocrine diseases.

• The branch of medicine that studies the endocrine disorders is known as endocrinology.

The List of Endocrine Diseases

• The following table illustrates the endocrine diseases −

Glucose Homeostasis Disorders
Diseases	Types	Result
Diabetes Mellitus	Type 1 Diabetes	Increases sugar levels
	Type 2 Diabetes
	Gestational Diabetes
Hypoglycemia	Idiopathic hypoglycemia	Decreases sugar level (below normal)
	Insulinoma
Glucagonoma	Cause: Because of the overproduction of glucagon hormone	tumor of the pancreas
Thyroid Disorders
Goiter	Cause: deficiency of iodine	swelling of the neck or larynx
Hyperthyroidism (excessive production of thyroid hormone)	Graves-Basedow disease	Muscle weakness, sleeping problems, diarrhea, weight loss, etc.
	Toxic multinodular goitre
Hypothyroidism
(low release of thyroid hormone)		Poor ability to tolerate cold, a feeling of tiredness, constipation, depression, and weight gain
Thyroiditis	Hashimoto’s thyroiditis	Inflammation of the thyroid gland
Thyroid cancer		Nodule in the thyroid region of the neck
Metabolic Bone Disease
Parathyroid gland disorders	Primary hyperparathyroidism	Alterations in the blood calcium levels and bone metabolism
	Secondary hyperparathyroidism
	Tertiary hyperparathyroidism
	Hypoparathyroidism
Osteoporosis		Bone weakness
Paget's disease of bone		Weakening of bones
Rickets and Osteomalacia		Child disease (because of vitamin D deficiency)
Pituitary Gland Disorders
Diabetes insipidus		Excessive thirst and excretion of large amounts of severely dilute urine
Hypopituitarism
Pituitary tumors	Pituitary adenomas
	Prolactinoma
	Acromegaly
	Cushing's disease
Sex Hormone Disorders
Intersex disorders	Hermaphroditism
	Gonadal dysgenesis
	Androgen insensitivity syndromes
Genetic and chromosomal disorders	Kallmann syndrome
	Klinefelter syndrome
	Turner syndrome
Acquired disorders	Ovarian failure
	Testicular failure
Disorders of Puberty	Delayed puberty
	Precocious puberty
Menstrual function or fertility disorders	Amenorrhea
	Polycystic ovary syndrome

Biology - Carbohydrate

Introduction

• Consisting of oxygen (O), carbon (C), and hydrogen (H), carbohydrate is a biological molecule.

• Carbohydrate is one of the essential elements for the living organisms, as it plays various important roles.

• Carbohydrate is the main source of energy, as about two-third energy requirement of living beings is fulfilled by it.

• Glucose, sugar, and starch are the important examples of carbohydrate.

Source of Carbohydrate

• Carbohydrates naturally are occurring in wide variety of foods, such as −

  • Wheat

  • Maize

  • Rice

  • Potatoes

  • Sugarcane

  • Fruits

  • Table sugar

  • Bread

  • Milk

• Sugar that we eat in our everyday life is mainly sucrose (table sugar).

• Sucrose is added in many food items while preparing, e.g. jam, biscuits, cakes, energy drinks, etc.

• Further, many fruits naturally contain glucose and fructose.

• Glycogen is another type of carbohydrate that found in the liver and muscle.

• Cellulose found in the cell wall of plant cells is carbohydrate.

Types of Carbohydrate

• The following table illustrates major categories and sub-categories of carbohydrate −

Class	Subgroup	Components
Sugar	Monosaccharides	Glucose, fructose, xylose, galactose
	Disaccharides	Sucrose, lactose, maltose, trehalose
	Polyols	Sorbitol, mannitol
Oligosaccharides	Malto-oligosaccharides	Maltodextrins
	Other oligosaccharides	Raffinose, stachyose, fructo-oligosaccharides
Polysaccharides	Starch	Amylose, amylopectin, modified starches
	Non-starch polysaccharides	Cellulose, hemicellulose, pectins, hydrocolloids

Functions of Carbohydrate

• Following are the major functions of carbohydrates −

  • Carbohydrates provide energy required for the proper function of the body.

  • Carbohydrates also store food in the body for the contingency period.

  • Carbohydrates form nucleic acids.

  • Carbohydrates also support skeleton system of animals.

  • Carbohydrates provide sweetness and flavor.

  • Carbohydrates break down the fatty acid.

Biology - Proteins

Introduction

• Proteins, which are basically biomolecules, play wide range of functions in the body of a living organism.

• Proteins are made up of tiny elements of different types of amino acids.

• A sequence of amino acid residues in a protein is known particularly by the sequence of a gene; gene is encoded in the genetic code.

• After formation, proteins exist for a fixed period of time and are then degraded and recycled.

• The proteins get recycled by the cell's machinery by the process of protein turnover.

• Most of the proteins contain linear polymers made up of series of up to 20 different L-α-amino acids.

• The amino acids in a polypeptide chain are connected by peptide bonds (see the image given below).

• The peptide bond, usually, has two resonance forms, which contribute some double-bond characters.

Protein Structure

• Most of the proteins illustrate unique 3-dimensional structures (see image given below).

• However, proteins have not a rigid structure, but rather, proteins may vary between several related structures especially when they perform their functions.

Functions of Proteins

• Following are the major functions of proteins −

  • In the cell, proteins are the chief actors that carry out the duties defined by the information encoded in genes.

  • Proteins are essential for the overall body growth.

  • Proteins play a role of bio-catalyst and biotic regulator.

  • Proteins provide instant energy especially during the emergency period.

  • Proteins help in catalyzing the metabolic reactions.

  • Proteins are the essential elements in DNA replication.

  • Proteins actively help in transporting molecules from one location to another in the body.

Types of Protein

• Following are the major types of protein −

  • Enzymes − enzymes play important role especially during the breakdown of molecules. Enzymes are also required for the digestion and growth of the cell.

  • Structural Proteins − such type of proteins provide strength to cells, tissues, and organs.

  • Signaling Proteins − Such proteins facilitate cells to communicate with each other by providing signals.

  • Defensive Proteins − Such proteins help organisms to fight with infection and support damaged tissue in healing fast.

  • Hormone − Some hormones are proteins that help in metabolic activities.

Biology - Fats

Introduction

• Fat is a significant foodstuff for many forms of life.

• Fats serve structural as well as metabolic functions.

• The fats are molecules made up of glycerol and fatty acid.

• Fat is an organic compound of hydrogen, carbon, oxygen.

• Based on the number and bonding of the carbon atoms, fats and oils, are categorized in the aliphatic chain.

Functions of Fats

• Following are the major functions of Fats −

  • Fat is a vital dietary requirement.

  • The fat is usually the stored source of energy in the body that remained store beneath the skin.

  • Fat acts a protective layer especially in the human body and provide protection.

  • Some of the vitamins such as vitamin A, vitamin D, vitamin E, and vitamin K are fat-soluble, which means they can only be absorbed, digested, and transported in conjunction with the fats.

  • Fats actively help in maintaining the healthy skin and hair.

  • Fats insulate body organs against external shock.

  • Fats also maintain body temperature.

  • Fats promote healthy cell function.

Types of Fats

• Following are the major types of Fats −

Unsaturated Fats

• The fats that remain in the liquid form at room temperature are known as unsaturated fats.

• Unsaturated fats are beneficial for health, as it improves blood cholesterol levels, stabilize heart beats, etc.

• Unsaturated fats are commonly found in vegetable oils, nuts, and many seeds.

Saturated Fats

• Saturated fats have no double bonds between the carbons found in its chain.

• Saturated fats can easily solidify and typically found in solid form at room temperature.

• Saturated fats are found in animals’ meat, cheese, ice cream, etc.

Biology - Vitamins

Introduction

• Vitamin is one of the most essential organic compounds that organisms require for the growth and maintenance of the body.

• Unlike other nutrients, vitamins are classified by their biological and chemical activity, instead of their structure.

• The term vitamin was derived from a compound word namely "vitamin."

• The Polish biochemist Kazimierz Funk, first used the compound word ‘vitamin’ in 1912.

• Usually, vitamins are represented by the English capital letters, e.g. A, B, C, E, etc.

• The body of a human being stores different vitamins widely; the vitamins A, D, and B12 are stored in substantial amounts, generally in the liver.

• Deficiency of vitamins causes disease.

• Based on solubility, vitamins are classified as water soluble vitamins and fat soluble vitamins.

• Water-soluble vitamins can dissolve easily in water.

• On the other hand, fat-soluble vitamins can be dissolved easily in fat.

• Further, fat-soluble vitamins get absorbed easily through the intestinal tract.

List of Vitamins

• By the time, thirteen vitamins are comprehensively recognized.

• The following table illustrates the list of vitamins with their properties −

Vitamins	Chemical Name	Solubility	Deficiency disease
Vitamin A	Retinol	Fat	Night blindness, keratomalacia, etc.
Vitamin B1	Thiamine	Water	Beriberi
Vitamin B2	Riboflavin	Water	Ariboflavinosis, glossitis, etc.
Vitamin B3	Niacin	Water	Pellagra
Vitamin B5	Pantothenic acid	Water	Paresthesia
Vitamin B6	Pyridoxine	Water	Anemia
Vitamin B7	Biotin	Water	Dermatitis
Vitamin B9	Folic acid	Water	Megaloblastic anemia
Vitamin B12	Cyanocobalamin	Water	Pernicious anemia
Vitamin C	Ascorbic acid	Water	Scurvy
Vitamin D	Cholecalciferol	Fat	Rickets
Vitamin E	Tocopherols	Fat	Hemolytic anemia (in children)
Vitamin K	Phylloquinone	Fat	Bleeding diathesis

Functions of Vitamins

• Vitamins have different biochemical functions, significant of them are −

  • Like hormone, vitamin D regulates and helps in mineral metabolism

  • Vitamin D also regulates and helps cells and tissue growth

  • Vitamin C and vitamin E act as antioxidants

  • Vitamin B complex acts as co-enzymes or the precursors of enzymes and helps them as catalysts in metabolic activities.

Biology - Minerals

Introduction

• Mineral is a chemical element essentially required as nutrient for the proper functioning of the body and healthy life.

• Minerals cannot be made by living organisms, rather it occurs in the Earth naturally.

• Most of the minerals that required for the proper function of a human life come from green plants, animals, and from drinking water.

• Calcium, phosphorus, potassium, sodium, and magnesium are the five major minerals in the human body.

• Minerals are present in the blood of a healthy human being at certain mass.

Major Minerals

• The following table illustrates the list of major minerals along with their salient features −

Minerals	Deficiency disease	Sources
Potassium	Hypokalemia	Sweet potato, potato, tomato, lentils, banana, carrot, orange, etc.
Chlorine	Hypochloremia	Table salt
Sodium	Hyponatremia	Table salt, sea vegetable, milk, etc.
Calcium	Hypocalcaemia	Eggs, canned fish, dairy products, nuts, etc.
Phosphorus	Hypophosphatemia	Red meat, fish, bread, dairy products, rice, oats, etc.
Magnesium	Hypomagnesemia	Legumes, nuts, seeds, spinach, peanut butter, etc.
Iron	Anaemia	Meat, seafood, beans, nuts, etc.
Zinc	Hair loss, diarrhea	Red meat, nuts, dairy products, etc.
Manganese	Osteoporosis	Grains, nuts, leafy vegetables, legumes, seeds, tea, coffee
Copper	Copper deficiency	Seafood, oysters, nuts, seeds
Iodine	Goitre	Grains, eggs, iodized salt
Chromium	Chromium deficiency	Broccoli, grape juice, meat, etc.
Molybdenum	Molybdenum deficiency	Legumes, whole grains, nuts
Selenium	Selenium deficiency	Brazil nuts, meat, seafoods, grains, dairy products, etc.

Biology - Genetic Terminology

• The following table illustrates the major Genetic Terminologies along with their brief explanations −

Sr.No.	Terminology & Definition/Description
1	Allele An alternative form of a gene
2	Amorph A silent gene
3	Angelman syndrome a rare genetically inherited form of mental retardation
4	Autosome Synonymous with somatic chromosomes
5	Chimera An exceptionally rare person composed of the cells derived from different zygotes
6	Chromosome Rod-shaped or thread-like structures located within the cell nucleus that carry genes encoded by DNA
7	Cloned gene A recombinant DNA molecule along with the gene of interest
8	Consanguinity Having a common ancestor, i.e., blood relations
9	Crossing over The exchange of genetic material between a pair of homologous chromosomes
10	Cross-pollination Mating of two genetically different plants (but of the same species).
11	Dizygotic twins Twins produced from two separate ova, which are separately fertilized
12	Deoxyribonucleic acid (DNA) Composed of nucleic acids, DNA encodes the genes that facilitate genetic information to be passed to offspring.
13	Evolution Genetic change in a population of organisms over period of time
14	Gamete A reproductive sex cell (i.e. ovum or sperm)
15	Gene Units of inheritance typically occurring at specific locations (a chromosome)
16	Gene Pool All of the genes in all of the individuals in a breeding population
17	Gene Flow The transference of genes from one population to another
18	Genetic Drift Evolution, or change in gene pool frequencies, resulting from a random chance
19	Genetics Study of gene structure, action, and the patterns of inheritance of traits from parent to offspring
20	Genome The full genetic complement of a species
21	Genomic imprinting The epigenetic phenomenon by which certain genes are expressed in a parent-of-origin-specific manner
22	Genotype Genetic constitution of a cell (of an individual organism)
23	Gout Genetically inherited metabolic disorder (or a type of arthritis)
24	Hemophilia Genetic disorder (largely inherited), problem in blood clotting
25	Heterozygous A cell containing two different alleles of a gene
26	Huntington's disease An inherited disorder that results into death of brain cells
27	Hybrid Combining the qualities of two animals or plants of different breeds, varieties, species (also known as crossbreed)
28	Mutation Change that occurs in DNA sequence
29	Observable characteristics or traits of an individual resulting from the interaction between genotype and the environment
30	Pleiotropy When one gene influences two or more apparently unrelated phenotypic traits
31	Psoriasis An inherited disease categorized by recurring thick, reddish patches on skin
32	Syntenic Genes occurring on the same chromosome
33	Zygote The fertilized egg is known as zygote

Organisms & their Chromosome Counts

• The following table illustrates the number of chromosomes present in respective organisms −

Organism	Scientific Name	No. of Chromosomes
Carp		104
Red viscacha rat	Tympanoctomys barrerae	102
Shrimp	Penaeus semisulcatus	86-92
Great white shark	Carcharodon carcharias	82
Pigeon	Columbidae	80
Turkey	Meleagris	80
African wild dog	Lycaon pictus	78
Chicken	Gallus gallus domesticus	78
Coyote	Canis latrans	78
Dhole	Cuon alpinus	78
Dingo	Canis lupus dingo	78
Dog	Canis lupus familiaris	78
Dove	Columbidae	78
Golden Jackal	Canis aureus	78
Gray wolf	Canis lupus	78
Maned wolf	Chrysocyon brachyurus	76
American black bear	Ursus americanus	74
Asiatic black bear	Ursus thibetanus	74
Brown bear	Ursus arctos	74
Polar bear	Ursus maritimus	74
Sloth bear	Melursus ursinus	74
Sun bear	Helarctos malayanus	74
Bat-eared fox	Otocyon megalotis	72
Black nightshade	Solanum nigrum	72
White-tailed deer	Odocoileus virginianus	70
Elk (Wapiti)	Cervus canadensis	68
Red deer	Cervus elaphus	68
Gray fox	Urocyon cinereoargenteus	66
Raccoon dog	Nyctereutes procyonoides	66
Chinchilla	Chinchilla lanigera	64
Echidna		63/64
Fennec fox	Vulpes zerda	64
Horse	Equus ferus caballus	64
Spotted spunk	Spilogale x	64
Mule		63
Donkey	Equus africanus asinus	62
Giraffe	Giraffa camelopardalis	62
Gypsy moth	Lymantria dispar dispar	62
Bengal fox	Vulpes bengalensis	62
American bison	Bison bison	60
Cow	Bos primigenius	60
Goat	Capra aegagrus hircus	60
Yak	Bos mutus	60
Elephant	Elephantidae	56
Gaur	Bos gaurus	56
Capuchin monkey	Cebus x	54
Sheep	Ovis orientalis aries	54
Water buffalo	Bubalus bubalis	50
Chimpanzee	Pan troglodytes	48
Gorilla	Gorilla	48
Orangutan	Pongo x	48
Human	Homo sapiens	46
Sable antelope	Hippotragus niger	46
Dolphin	Delphinidae Delphi	44
European rabbit	Oryctolagus cuniculus	44
Giant panda	Ailuropoda melanoleuca	42
Rat	Rattus norvegicus	42
Rhesus monkey	Macaca mulatta	42
Lion	Panthera leo	38
Pig	Sus	38
Tiger	Panthera tigris	38
Kangaroo		16
Yellowfever mosquito	Aedes aegypti	6
Spider mite		4-14
Jack jumper ant	Myrmecia pilosula	2
Honeybee	Apis mellifera	32

Biology - Viral Diseases

• The following table illustrates the diseases caused by virus −

Disease Name	Organs Affected	Transmission
Influenza	Respiratory Tract	Droplets
Adenovirus Infections	Lungs, Eyes	Droplets, Contact Droplets
Respiratory Syncytial Disease	Respiratory Tract	Droplets
Rhinovirus Infections	Upper Respiratory Tract	Droplets, Contact
Herpes Simplex	Skin, Pharynx, Genital organs	Contact
Chicken pox ( Varicella)	Skin, Nervous System	Droplets, Contact
Measles (Rubeola)	Respiratory Tract, Skin	Droplets, Contact
German Measles ( Rubella)	Skin	Droplets, Contact
Mumps (Epidemic Parotitis)	Salivary Glands, Blood	Droplets
Viral meningitis	Headache
Small Pox (Variola)	Skin, Blood	Contact, Droplets
Warts Kawasaki Disease	Skin
Yellow Fever	Liver, Blood	Mosquito
Dengue Fever	Blood, Muscles	Mosquito
Hepatitis A	Liver	Food, Water, Contact
Hepatitis B	Liver	Contact with body Fluids
NANB Hepatitis	Liver	Contact with body Fluids
Viral Gastroenteritis	Intestine	Food, Water
Viral Fevers	Blood	Contact, arthropods
Cytomegalovirus Disease	Blood, Lungs	Contact, Congenital transfer
Shingles (varicella zoster virus)	Skin
AIDS	T-lymphocytes	Contact with body Fluids
Rabies	Brain, Spinal cord	Contact with body Fluids
Polio	Intestine, Brain, Spinal Cord	Food, Water, Contact
Slow Virus Disease	Brain
Viral pneumonia	infection in lung
Arboviral Enephalitis	Brain	Arthropods
Ebola	Whole body	bodily fluids

Biology - Bacterial Diseases

• The following table illustrates the diseases caused by bacteria −

Disease Name	Bacteria Name	Affected organs
Cholera	Vibrio cholerae	Small intestine
Anthrax	Bacillus Anthrasis	Skin, lung, and bowel disease
Diphtheria	Corynebacterium diphtheriae	Mucous membranes of your nose and throat
Leprosy	Mycobacterium leprae	Skin
Botulism	Clostridium botulinum
Syphilis	Treponema pallidum	Genital part, lips, mouth, or anus
Tetanus	Clostridium tetani	Muscle (affected), nervous system
Trachoma	Chlamydia trachomatis	Eye
Tuberculosis	Mycobacterium tuberculosis	Lungs
Typhoid fever	Salmonella typhi	Almost of whole part of the body
Whooping cough	Bordetella	pertussis

Some Other Diseases

Disease Name	Caused by	Affected organs
Athlete’s foot	Epidermophyton floccosum (fungi)	Skin on the feet
Malaria	Plasmodium vivax (Protozoa)
Amoebic dysentery	Entamoeba histolytica	Intestine
Filariasis	Roundworms	Lymph vessels
Hookworm disease	Ancylostoma duodenale	Intestine and lungs
Roundworm disease	Ascaris lumbricoides	Intestine
Blood fluke disease	Schistossoma mansoni	Skin, lymph, liver, and spleen

Biology - Branches of Biology

• The following table illustrates the different branches of biology with their brief description −

Branch	Studies
Anatomy	Study of the internal structure of an organism
Aerobiology	Study of airborne microorganisms
Agronomy	Study of soil management and crop production
Agrostology	Study of grasses
Araneology	Study of spiders
Actinobiology	Study of the effects of radiation upon living organisms
Angiology	Study of the diseases of the circulatory system and of the lymphatic system
Bioinformatics	of collecting and analyzing complex biological data including genetic codes through computer technology
Biotechnology	Use of cellular and biomolecular processes to develop technologies and products, which ultimately help to improve human lives and the health of the planet.
Biochemistry	Study of chemical and physio-chemical processes and substances, which occur within the living organisms.
Batrachology	Study of amphibians including frogs and toads
Bioclimatology	Study of the interactions between the biosphere and the Earth's atmosphere on time scales
Botany	Study of plants
Bryology	Study of mosses and liverworts
Cytology	Study of the structure and function of plant and animal cells.
Cryobiology	Study of biological material or systems at temperatures below normal
Chromatology	Study of colors
Cetology	Study of whales, dolphins, and porpoises
Chronobiology	Study of periodic (cyclic) phenomena in living organisms
Conchology	Study of mollusc shells
Chondrology	Study of the cartilage
Craniology	Study of the shape and size of the skulls of different human races
Cardiology	Study of the diseases and abnormalities of the heart
Dendrology	Study of trees
Dermatology	Study of skin
Desmology	Study of structures and anatomy of ligaments
Embryology	Study of the prenatal development of gametes (sex cells), fertilization, and development of embryos and fetuses.
Ecology	Study of interactions among organisms and their environment
Ethology	Study of animal behaviors
Entomology	Study of insects
Etiology	study of causation, or origination (largely of diseases)
Epigenetics	Study of the changes in a chromosome that affect gene activity and expression (specifically phenotype change and NOT genotype changes)
Ethnobotany	Study of a geographic region's plants and their possible uses through the traditional knowledge
Forestry	Study creating, managing, using, conserving, and repairing forests
Gynaecology	Study of medical practice that deals with the health of the female reproductive systems
Gerontology	Study of the process of ageing and old age problems
Genetics	Study of genes, genetic variation, and heredity
Genecology	Study of genetic variation of species and communities in comparison to their population
Genetic engineering	Study of developing technique of direct manipulation of an organism's genome by using biotechnology
Horticulture	Study of practice of garden cultivation
Helminthology	Study of parasitic worms
Herpetology	Study of reptiles (including amphibians)
Hepatology	Study of liver
Haematology	Study of blood, its problems and treatments
Histology	Study of tissue
Ichthyology	Study of fishes
Ichnology	Study of traces of organismal behavior
Kalology	Study of beauty
Lepidopterology	Study of moths and the butterflies
Limnology	Study of inland waters (emphasizing of biological, physical, and chemical features)
Limnobiology	Study of animals and plants of fresh water
Molecular biology	Study of the structure and function of the macromolecules (such as proteins and nucleic acids)
Malacology	Study of the Mollusca
Mycology	Study of fungi
Nephrology	Study of kidney
Neurology	Study of nervous system
Ornithology	Study of birds
Ophthalmology	Study of eye
Osteology	Study of skeleton system
Palaeozoology	Study of animal fossils
Physiology	Study of normal functioning of living organisms
Pathology	Study of disease and a major field in modern medicine and diagnosis
Palaeobotany	Study of plant fossils
Phycology	Study of algae
Pomology	Study of fruits
Phrenology	Study of specific functions of brain
Sedimentology	Study of sand, silt, clay, etc.
Serpentology	Study of snakes
Saurology	Study of lizards
Sitology	Study of food, diet, and nutrition
Spelaeology	Study of caves
Taxonomy	Study of nomenclature (classification) of animals
Trophology	Study of nutrition (for healthy health)
Traumatology	Study of wounds and injuries caused by accidents (or violence)
Zoogeography	Study of distribution of animals
Zymology	Study of the biochemical process of fermentation and its practical uses
Zootechny	Study of domestication of animals (includes breeding, genetics, nutrition, and housing)
Zoonosology	Study of animal diseases'
Zoology	Study of animals

Biology - Inventions & Discoveries in Biology

• The following table illustrates important inventions and discoveries in Biology −

Name of inventions/discoveries	Discoverers & Inventors
Systemic circulation of blood	William Harvey
Observation of microorganisms	Antony van Leeuwenhoek
Sex hormones	Eugen Stainak
Simple microscope	Anton van Leeuwenhoek
Stethoscope	René Laennec
First test tube baby	Robert Edward and Patrick Steptoe
Vaccination	Edward Jenner
Vitamin	Casimir Funk
CT scan	Godfrey Hounsfield & Allan Cormack
DNA	Rosalind Franklin and Maurice Wilkins
DNA Structure	James Watson and Francis Crick
DNA Fingerprinting	Alec Jeffreys
Electrocardiogram (ECG)	Willem Einthoven
5 kingdom classification	R. H. Whittaker
Genetic code	Marshall Nirenberg and Heinrich J. Matthaei
Genetic drift	Sewall Wright
Father of heart transplantation	Norman Shumway
Heart transplantation first performed	Christiaan Barnard
Hormone	William Bayliss
Insulin	Frederick Banting and Charles H. Best
Malaria Parasite	Charles Louis Alphonse Laveran
Magnetic Resonance Imaging (MRI)	Damadian
Open heart surgery	Dr. Daniel Hale Williams. And Dr. Daniel Williams
Penicillin	Alexander Fleming
Polio vaccine	Jonas Salk and a team
Rh factor in human blood	Dr. Alexander S. Wiener and Karl Landsteiner
Cancer	Hippocrates
Blood group (ABO group)	Karl Landsteiner
Binomial nomenclature	Carl Linnaeus
Bacteria (& protozoa)	Van Leeuwenhoek
Aspirin	Felix Hoffmann at Bayer in Germany
Jarvik-7 (first artificial heart)	Willem Johan Kolff and Robert Jarvik
Anthrax vaccine	Pasteur
Amoeba	August Johann Rösel von Rosenhof
Oxygen in respiration and photosynthesis	Joseph Priestley, Antoine Lavoisier and Jan Ingenhousz
Animal electricity	Luigi Galvani
Cell	Robert Hooke
Cell Theory	Schleiden and Schwann
Chromosomes	Hofmeister
Chioroplast	Schimper
Mitochondria	Kolliker
Nucleus	Robert Brown
Nucleoplasm	Strasburger
Enzyme	Anselme Payen
Mitosis	Walther Flemming
Meiosis	Oscar Hertwig
Mutations	Thomas Hunt Morgan and Lilian Vaughan Morgan
Virus	Dmitri Ivanovsky & Martinus Beijerinck

Nobel Prize in Biology

Introduction

Gerty Cori

• Cori, a Czech-American biochemist, was the first woman to be awarded the Prize in Physiology or Medicine.

• She received the prize in 1947.

• She was the third woman and first American woman who won a Nobel Prize in science.

• She received the award for her work namely “the mechanism by which glycogen—a derivative of glucose—is broken down in muscle tissue into lactic acid and then resynthesized in the body and stored as a source of energy (known as the Cori cycle).”

• The following table illustrates some of the eminent Nobel Prize winners −

Name	Country/Year	Work
Emil Adolf von Behring	Germany (1901)	Serum therapy
Sir Ronald Ross	UK (1902)	Worked on malaria
Ivan Petrovich Pavlov	Russia (1904)	Physiology of digestion
Albrecht Kossel	Germany (1910)	Cell Chemistry
Allvar Gullstrand	Sweden (1911)	Dioptrics of the eye
Alexis Carrel	France (1912)	Vascular suture and the transplantation of blood vessels and organs
Archibald Vivian Hill	UK (1922)	Production of heat in the muscle
Sir Frederick Grant Banting & John James Rickard Macleod	Canada & UK (1923)	Discovery of insulin
Karl Landsteiner	Austria (1930)	Discovery of human blood groups
Thomas Hunt Morgan	US (1933)	Role played by the chromosome in heredity
Carl Peter Henrik Dam	Denmark (1943)	Discovery of vitamin K
Sir Alexander Fleming	UK (1945)	Discovery of penicillin and its curative effect in various infectious diseases
Sir Ernst Boris Chain	UK (1945)
Howard Walter Florey	Austria (1945)
Carl Ferdinand Cori	US (1947)	Discovery of the course of the catalytic conversion of glycogen
Gerty Theresa Cori, née Radnitz
Max Theiler	South Africa (1951)	Yellow fever
Selman Abraham Waksman	US (1952)	Discovery of streptomycin, the first antibiotic effective against tuberculosis
Joshua Lederberg	US (1958)	Genetic recombination
Peyton Rous	US (1966)	Discovery of tumor-inducing viruses
Charles Brenton Huggins	US (1966)	Hormonal treatment of prostatic cancer
Har Gobind Khorana	India & US (1968)	Interpretation of the genetic code and its function in protein synthesis
Marshall W. Nirenberg	US (1968)
Robert W. Holley	US (1968)
Albert Claude	Belgium (1974)	Structural and functional organization of the cell
Christian de Duve
George E. Palade	Romania (1974)
Baruch S. Blumberg	US (1976)	Origin and dissemination of infectious diseases
D. Carleton Gajdusek
Michael S. Brown	US (1985)	Regulation of cholesterol metabolism
Joseph L. Goldstein
Sir Richard J. Roberts	UK (1993)	Discovery of split genes
Phillip A. Sharp	US (1993)
Paul Lauterbur	US (2003)	Magnetic resonance imaging
Sir Peter Mansfield	UK (2003)
Andrew Z. Fire	US (2006)	Discovery of RNA interference
Craig C. Mello
Harald zur Hausen	Germany (2008)	Human papilloma viruses causing cervical cancer
Françoise Barré-Sinoussi	France (2008)	Discovery of human immunodeficiency virus
Luc Montagnier
Sir Robert G. Edwards	UK (2010)	Development of in vitro fertilization
Tu Youyou	China (2015)	Discovery of a novel therapy against Malaria
Yoshinori Ohsumi	Japan (2016)	Mechanisms for autophagy